Fusion Meso

F-MELACLEAR 5 x 10ml

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Topical Use Only

Active Ingredients: Niacinamide, Tranexamic Acid, Resorcinol, Glutathione, Arbutin

F-MELACLEAR is the corrective pigment vial, and the most complete in the range: five actives spread across the whole melanin pathway. Tranexamic acid interrupts the inflammatory signal that starts it, arbutin and resorcinol both inhibit tyrosinase, the enzyme that drives it, glutathione acts on the pigment already made, and niacinamide blocks its transfer into the surface cells.

Attacking one stage rarely holds, this covers four. For defined patches of darker pigment, and the vial to begin a melasma protocol with, holding the result afterwards with F-TRANEXAMIC.

A sterile solution supplied in 10ml vials, for topical application with microneedling and transdermal delivery devices.


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The Formula

F-MELACLEAR

How It Works

Pigment production is a sequence, not a single event. A signal starts it, an enzyme drives it, the pigment forms, and then it transfers into the surface cells where it becomes visible. Treatments that attack one stage of that sequence often disappoint, because the stages before and after carry on regardless.

This vial covers four of them. Tranexamic acid interrupts the inflammatory signal that begins the process. Arbutin and resorcinol both inhibit tyrosinase, the enzyme that drives pigment production, two different actives on the same target. Glutathione acts on the pigment already made. Niacinamide blocks its transfer into the keratinocytes at the surface.

That spread is what makes it the corrective vial in the range, and why it can shift marks that single-ingredient treatments leave behind.

Key Active Ingredients

  • Tranexamic Acid: interrupts the inflammatory signal that starts pigment production.
  • Arbutin: inhibits tyrosinase, the enzyme that drives pigment production.
  • Resorcinol: inhibits the same enzyme by a different route, working alongside the arbutin.
  • Glutathione: acts on pigment that has already been made.
  • Niacinamide: blocks the transfer of pigment into the keratinocytes at the surface.

What Makes It Different

  • Five actives across four stages of the melanin pathway, the most complete pigment formulation in the range.
  • Two separate tyrosinase inhibitors rather than one, working on the same target by different routes.
  • The corrective vial: the one to begin with when pigment is well established.

Key Benefits

What this product does for the skin

Defined Patches

Established Pigment

For defined patches of darker pigment, where the mark is well established rather than diffuse.

Coverage

Four Stages At Once

Five actives across four stages of the pathway, rather than pushing at a single point.

Persistence

Shifts Stubborn Marks

Can shift marks that single-ingredient treatments leave behind.

Protocol

Where Melasma Starts

The vial to begin a melasma protocol with, before holding the result with F-TRANEXAMIC.

Other Info

F-MELACLEAR

Choosing Between Vials

  • Begin a melasma protocol with F-MELACLEAR, then hold the result with F-TRANEXAMIC.
  • For diffuse pigment spread across the skin rather than in defined patches, F-TRANEXAMIC is the choice.
  • For sun damage, post-breakout marks and dull, thickened skin, F-RADIANCE takes the renewal route.
  • Where pigment sits on skin that has also lost volume, F-HA GLOW treats both.

Product Details

  • Pack: 5 x 10ml sterile vials.
  • Concern: melasma and localised pigmentation.
  • Suitable across the full age range.
  • Store at room temperature, keep dry and out of direct sunlight.

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